Overexpression of MMP14 is associated with poor prognosis and immune cell infiltration in colon cancer

Overexpression of MMP14 is associated with poor prognosis and immune cell infiltration in colon cancer

IntroductionColorectal cancer (CRC) poses a significant risk of recurrence and distant metastases. This study investigated the regulatory role of Matrix metalloproteinase-14 (MMP14) in immune function and its impact on CRC prognosis.Methodswe performed transcriptome sequencing on tumor and adjacent...

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Bibliographic Details
Main Authors: Na Li, Nan Zhang, Guanghui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
MMP14
prognosis
immune cell infiltration
CRC
machine learning
RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1564375/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1564375/full

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