ATP6V0B promotes the tumorigenesis of bladder cancer by activating PAQR4/PI3K/AKT signaling

Abstract Background ATPase H+ transporting V0 subunit b (ATP6V0B) is an essential component of the vacuolar ATP multi-protein complex (V-ATPase) associated with energy metabolism. However, information on its role and mechanism of action in bladder cancer (BCa) and other tumors is not clear. Methods...

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Bibliographic Details
Main Authors: Xinsheng Wang, Yanqing Qu, Yanbo Sun, Tong Yang, Wei Wang, Xinmeng Dou, Yong Jia
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-025-14183-z
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