Toward the DNA methylation haplotype map of 11 common solid cancers

Summary: In heterogeneous tumors, adjacent CpG sites form methylation haplotype blocks (MHBs), genomic regions where methylation status reflects local epigenetic concordance. While MHBs have been implicated in gene dysregulation, their pan-cancer dynamics and clinical relevance remain unclear. We pr...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhiqiang Zhang, Yuyang Hong, Shirong Zhang, Xin Zhu, Leiqin Liu, Xiqi Liao, Hongcang Gu, Hai Fang, Jiantao Shi
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725009684
Tags: Add Tag
No Tags, Be the first to tag this record!