Enhancement of Human Immunodeficiency Virus-Specific CD8<sup>+</sup> T Cell Responses with TIGIT Blockade Involves Trogocytosis

Natural killer (NK) and CD8<sup>+</sup> T cell function is compromised in human immunodeficiency virus type 1 (HIV-1) infection by increased expression of inhibitory receptors such as TIGIT (T cell immunoreceptor with Ig and ITIM domains). Blocking inhibitory receptors or their ligands w...

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Bibliographic Details
Main Authors: Nazanin Ghasemi, Kayla A. Holder, Danielle P. Ings, Michael D. Grant
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/13/12/1137
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