Structural modification of Naproxen; physicochemical, spectral, medicinal, and pharmacological evaluation

Structural modification of Naproxen; physicochemical, spectral, medicinal, and pharmacological evaluation

Naproxen (Nap), a widely used nonsteroidal anti-inflammatory drug (NSAID), effectively reduces inflammation, pain, and fever by inhibiting cyclooxygenase enzymes (i.e., COX-1 and COX-2). However, its therapeutic use is often limited by significant adverse effects, including gastrointestinal hemorrha...

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Bibliographic Details
Main Authors: Md Omor Farque, Rahat Moinul Islam, Md Ferdous Rahman Joni, Mimona Akter, Shilpy Akter, Mohammad Didarul Islam, MD Jubaer Bin Salim, Ahamed Abdul Aziz, Emranul Kabir, Monir Uzzaman
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Naproxen
Cyclooxygenase
Physicochemical and spectral analysis
Medicinal and toxicological assessment
Online Access:http://www.sciencedirect.com/science/article/pii/S235291482500005X
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