LCZ696, an angiotensin receptor-neprilysin inhibitor, ameliorates epithelial-mesenchymal transition of peritoneal mesothelial cells and M2 macrophage polarization

LCZ696, an angiotensin receptor-neprilysin inhibitor, ameliorates epithelial-mesenchymal transition of peritoneal mesothelial cells and M2 macrophage polarization

Aims To investigate the effects and mechanisms of LCZ696, an angiotensin receptor-neprilysin inhibitor (ARNI), on epithelial-mesenchymal transition (EMT) of peritoneal mesothelial cells and on macrophage M2 polarization.Methods We examined the effects of LCZ696 in a 4.25% high glucose peritoneal dia...

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Bibliographic Details
Main Authors: Yan Hu, Canxin Zhou, Qin Zhong, Xialin Li, Jinqing Li, Yingfeng Shi, Xiaoyan Ma, Daofang Jiang, Yi Wang, Shougang Zhuang, Na Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
LCZ696
epithelial-mesenchymal transition
M2 macrophage polarization
peritoneal fibrosis
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2392849
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https://www.tandfonline.com/doi/10.1080/0886022X.2024.2392849

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