Human macrophage pro‐inflammatory polarization in response to free cholesterol and cholesterol remnants

Abstract Atherosclerosis is a chronic inflammatory disease of the blood vessels caused by elevated levels of lipoproteins. The hyperlipoproteinemia triggers a series of cellular changes, particularly the activation of the macrophages, which play a crucial role in the development and progression of a...

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Bibliographic Details
Main Authors: Karel Paukner, Barbora Muffova, Hana Bartuskova, Jan Mareš, Libor Janousek, Jiri Fronek, Sona Kauerova, Ivana Kralova Lesna, Rudolf Poledne
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Physiological Reports
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Online Access:https://doi.org/10.14814/phy2.70367
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