The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo

The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo

Abstract Homocysteine (Hcy), a sulfur-containing amino acid derived from methionine, has been shown to be a significant and modifiable risk factor for various neurological disorders, including stroke, Parkinson’s disease, Alzheimer’s disease, and elderly depression. However, there is currently a lac...

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Bibliographic Details
Main Authors: Meng Wang, Xiaoshan Liang, Keqing Jin, Yinyue Liu, Suhui Luo, Qiang Zhang, Xuan Wang, Zhiping Dong, Xumei zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Homocysteine
N2a cells
Microarray analysis
Synaptic vesicle cycle
Neurotoxicity
Online Access:https://doi.org/10.1038/s41598-025-98306-3
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https://doi.org/10.1038/s41598-025-98306-3

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