Stereoselectivity in Enzymic Biotransformation of Chiral and Achiral 1,3-Dihydro-2H-1,4-Benzodiazepin-2-ones
Enzymic biotransformation of chiral 1,4-benzodiazepin-2-ones (S and R forms) is found to be configuration dependent for hydroxylation in aromatic rings, but hydroxylation in position 3, as well as N1-demethylation prooved to be nonstereospecific.
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
1974-05-01
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| Series: | CHIMIA |
| Online Access: | https://www.chimia.ch/chimia/article/view/9140 |
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