Three-Dimensional-Bioprinted Embedded-Based Cerebral Organoids: An Alternative Approach for Mini-Brain In Vitro Modeling Beyond Conventional Generation Methods

Three-Dimensional-Bioprinted Embedded-Based Cerebral Organoids: An Alternative Approach for Mini-Brain In Vitro Modeling Beyond Conventional Generation Methods

Cerebral organoids (cORGs) obtained from induced pluripotent stem cells (iPSCs) have become significant instruments for investigating human neurophysiology, with the possibility of simulating diseases and enhancing drug discovery. The current approaches require a strict process of manual inclusion i...

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Bibliographic Details
Main Authors: Rosalba Monica Ferraro, Paola Serena Ginestra, Miriam Seiti, Mattia Bugatti, Gabriele Benini, Luana Ottelli, William Vermi, Pietro Luigi Poliani, Elisabetta Ceretti, Silvia Giliani
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Gels
Subjects:
cerebral organoids
induced pluripotent stem cells
neural stem cells
hydrogel
3D bioprinting
tissue engineering
Online Access:https://www.mdpi.com/2310-2861/11/4/284
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