Dihydroartemisinin targets the miR-497-5p/SOX5 axis to suppress tumor progression in non-small cell lung cancer

Dihydroartemisinin targets the miR-497-5p/SOX5 axis to suppress tumor progression in non-small cell lung cancer

IntroductionNon-small cell lung cancer (NSCLC) remains a lethal malignancy with limited therapeutic options. Although dihydroartemisinin (DHA) exhibits anticancer properties, its mechanisms in NSCLC are incompletely understood. This study investigated the role of the miR-497-5p/SOX5 axis in mediatin...

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Main Authors: Qing-Hua Yin, Qiang Zhou, Jian-Bing Hu, Jie Weng, Er-Dong Shen, Fang Wen, Song-Lian Liu, Lei-Lan Yin, Ya-Jun Tong, Ling Long, Ke-Wei Tang, Si-Te Bai, Lu-Di Ou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
dihydroartemisinin (DHA)
non-small cell lung cancer (NSCLC)
miR-497-5p
SOX5
anticancer activity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1605531/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1605531/full

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