Intact type I Interferon production and IRF7 function in sooty mangabeys.

Intact type I Interferon production and IRF7 function in sooty mangabeys.

In contrast to pathogenic HIV/SIV infections of humans and rhesus macaques (RMs), natural SIV infection of sooty mangabeys (SMs) is typically non-pathogenic despite high viremia. Several studies suggested that low immune activation and relative resistance of CD4+ central memory T-cells from virus in...

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Main Authors: Steven E Bosinger, Zachary P Johnson, Kathryn A Folkner, Nirav Patel, Tayebeh Hashempour, Simon P Jochems, Perla M Del Rio Estrada, Mirko Paiardini, Rongtuan Lin, Thomas H Vanderford, John Hiscott, Guido Silvestri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003597&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003597&type=printable

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