Enhancing DOX efficacy against NSCLC through UDCA-mediated modulation of the TGF-β/MAPK autophagy pathways

Enhancing DOX efficacy against NSCLC through UDCA-mediated modulation of the TGF-β/MAPK autophagy pathways

Abstract Lung carcinoma, predominantly manifested as non-small cell lung cancer (NSCLC), significantly contributes to oncological mortality, underscoring an imperative for novel therapeutic paradigms. Amidst this context, the present investigation delineates the synergistic potentiation of doxorubic...

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Bibliographic Details
Main Authors: Ying Li, Helian Zhao, Zhoumin Shen, Yao Zheng, Yuanyuan Jiang, Ying Song, Yimin Cai
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Autophagy
Chemotherapy
Non-small cell lung cancer
Ursodeoxycholic acid
Doxorubicin
TGF-β/MAPK pathway
Online Access:https://doi.org/10.1038/s41598-024-73736-7
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https://doi.org/10.1038/s41598-024-73736-7

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