Safety and clinical efficacy of Relmacabtagene autoleucel (relma-cel) for systemic lupus erythematosus: a phase 1 open-label clinical trialResearch in context
Summary: Background: Systemic lupus erythematosus (SLE) is a classic systemic autoimmune disease mediated by autoantibodies. Chimeric antigen receptor T (CAR-T) cell therapy, known for its success in cancer, has shown promise in achieving durable B cell depletion and long-term remission in SLE. Rel...
Saved in:
| Main Authors: | Jinhui Shu, Wei Xie, Chunli Mei, Anqi Ren, Sha Ke, Meilin Ma, Zisong Zhou, Yu Hu, Heng Mei |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
|
| Series: | EClinicalMedicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589537025001610 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Skin lesions in systemic lupus erythematosus. Part 2: clinical and histological features
by: A. A. Shumilova, et al.
Published: (2022-08-01) -
Clinical and laboratory relationships in patients with different variants of the course of systemic lupus erythematosus
by: V. A. Lila
Published: (2020-03-01) -
Lupus nephritis as a specific clinical and immunological phenotype of systemic lupus erythematosus
by: E. A. Aseeva, et al.
Published: (2022-12-01) -
Clinical variants of skin and mucous membrane lesions in systemic lupus erythematosus with juvenile onset
by: M. I. Kaleda, et al.
Published: (2023-04-01) -
Flare of bullous lupus erythematosus in patients treated with anifrolumab for discoid lupus erythematosus: 2 cases
by: Cécile Lesort, MD, et al.
Published: (2025-04-01)