Reverse vaccinology and immunoinformatics approaches for multi-epitope vaccine design against Klebsiella pneumoniae reveal a novel vaccine target protein

Reverse vaccinology and immunoinformatics approaches for multi-epitope vaccine design against Klebsiella pneumoniae reveal a novel vaccine target protein

Klebsiella pneumoniae (K. pneumoniae), a Gram-negative pathogen, is a leading cause of hospital-acquired infections in Sudan and worldwide. The emergence of multidrug-resistant (MDR) strains has severely limited treatment options, underscoring the urgent need for an effective vaccine. In this study,...

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Bibliographic Details
Main Authors: Mayada M. Elfadil, Samah Omer A. Samhoon, Moaaz M. Saadaldin, Sabah A.E. Ibrahim, Ahmed Abdelghyoum M. Mohamed, Omnia H. Suliman, Osama Mohamed, Nadzirah Damiri, Mohd Firdaus-Raih, Sofia B. Mohamed, Qurashi. M. Ali
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Immunoinformatics
Reverse Vaccinology
K. pneumoniae
Multi-Epitope Vaccine
Iron Acquisition Proteins
FyuA
Online Access:http://www.sciencedirect.com/science/article/pii/S1687157X2500054X
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