Reduced SARS-CoV-2 vaccine-specific antibody response associated with high clozapine doses in schizophrenia spectrum disorders

Reduced SARS-CoV-2 vaccine-specific antibody response associated with high clozapine doses in schizophrenia spectrum disorders

Background: Schizophrenia, affecting approximately 1 % of the population worldwide, is associated with increased mortality rates and a reduced life expectancy of 10–20 years. Approximately 30 % of cases are resistant to conventional antipsychotic treatments, necessitating the use of clozapine. Recen...

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Main Authors: Itziar Montalvo, Juan Francisco Delgado, Albert Rodrigo-Parés, Teresa Sagués, Antoni Berenguer-Llergo, Raquel Rodríguez-González, Indira Bhambi, Patricia Pontón, Germà Julià, Virginia Soria, Diego Palao, Javier Labad
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Schizophrenia
Clozapine
Antipsychotics
Immune response
Vaccination
Spike protein
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354625000742
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