Identification and validation of T cell senescence-related prognostic genes in gastric carcinoma and investigation of their potential regulatory mechanisms

Identification and validation of T cell senescence-related prognostic genes in gastric carcinoma and investigation of their potential regulatory mechanisms

Abstract Objective This study aimed to identify prognostic genes associated with immunosenescence in gastric carcinoma (GC) and to elucidate their mechanisms to provide new ideas for the clinical treatment of GC. Methods According to single cell data, clustering and annotation were conducted to acqu...

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Bibliographic Details
Main Authors: Jing Liu, Huiyu Wang, Fang Huang, Zhiqiang Hang, Pan Xu, Runjie Wang, Junying Xu
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Gastric carcinoma
Immunosenescence
Prognostic genes
Risk model
Single cell RNA sequencing data analysis
Online Access:https://doi.org/10.1007/s12672-025-02477-4
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https://doi.org/10.1007/s12672-025-02477-4

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