LncRNA PVT1 Facilitates Phenotypic Switching of Vascular Smooth Muscle Cells in Intracranial Aneurysms by Recruiting KDM1A to Reduce H3K9me2 Modification

LncRNA PVT1 Facilitates Phenotypic Switching of Vascular Smooth Muscle Cells in Intracranial Aneurysms by Recruiting KDM1A to Reduce H3K9me2 Modification

ABSTRACT This study explores the differential expression of lncRNA PVT1 in intracranial aneurysms (IAs) and its role in the phenotypic switching of vascular smooth muscle cells (VSMCs). PVT1 and ALOX5 expressions in the serum of IA patients and healthy controls were detected by qRT‐PCR. The diagnost...

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Bibliographic Details
Main Authors: Yu‐Fei Cheng, Wei Sun, Yi‐Xia Wang, Jia‐Jie Chen, Ya‐Sen Cao
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
ALOX5
intracranial aneurysms
KDM1A
LncRNA PVT1
vascular smooth muscle cells
Online Access:https://doi.org/10.1002/kjm2.70025
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https://doi.org/10.1002/kjm2.70025

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