Expanded and activated marrow-infiltrating lymphocytes exhibit potent antimyeloma activity against autologous multiple myeloma cells

Expanded and activated marrow-infiltrating lymphocytes exhibit potent antimyeloma activity against autologous multiple myeloma cells

Adoptive immunotherapy represents a promising treatment for multiple myeloma (MM), relying on the availability of sustainable tumor-specific cytotoxic T cells. This study generated potent ex vivo expanded and activated marrow-infiltrating lymphocytes (eMILs) from MM patients and evaluated their immu...

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Main Authors: Seo-Yeon Ahn, Manh-Cuong Vo, Van-Tan Nguyen, Van-Dinh-Huan Tran, Tien Nguyen Duc, Mihee Kim, Ga-Young Song, Jae-Sook Ahn, Deok-Hwan Yang, Hyeoung-Joon Kim, Sung-Hoon Jung, Je-Jung Lee
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Translational Oncology
Subjects:
Multiple myeloma
Immunotherapy
Marrow-infiltrating lymphocytes
Treatment
Bone marrow
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325002062
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