To What Extent Can Orbital Cellulitis Emergency Aspect Influence the Diagnosis of Maxillary Sinus Lymphoma?

We present a case of a 46-year-old woman admitted to the emergency department for acute swelling and erythema of the right eyelid for 3 days. Ophthalmological examination was notable for 10/10, P2 best visual acuity, and inflammatory periorbital edema, without exophthalmia nor extraocular motility d...

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Main Authors: Yousra Ajhoun, Ismail Aissa, Taoufik Abdellaoui, Yasmine Chaoui Roqai, Ilias Benchafai, Redouan Messaoudi, Rachid Zerrouk, Karim Reda, Abdelbarre Oubaaz
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2020/2304861
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author Yousra Ajhoun
Ismail Aissa
Taoufik Abdellaoui
Yasmine Chaoui Roqai
Ilias Benchafai
Redouan Messaoudi
Rachid Zerrouk
Karim Reda
Abdelbarre Oubaaz
author_facet Yousra Ajhoun
Ismail Aissa
Taoufik Abdellaoui
Yasmine Chaoui Roqai
Ilias Benchafai
Redouan Messaoudi
Rachid Zerrouk
Karim Reda
Abdelbarre Oubaaz
author_sort Yousra Ajhoun
collection DOAJ
description We present a case of a 46-year-old woman admitted to the emergency department for acute swelling and erythema of the right eyelid for 3 days. Ophthalmological examination was notable for 10/10, P2 best visual acuity, and inflammatory periorbital edema, without exophthalmia nor extraocular motility disturbance. Intraocular pressure was 14 mmHg and fundoscopic examination was not notable for any abnormality. Preseptal cellulitis diagnosis was made, and oral antibiotherapy was immediately started; after 72 hours, the patient did not improve and started complaining of pain on ocular movements. Brain and orbit MRI scan revealed right retroseptal cellulitis associated with homolateral pansinusitis. Intravenous antibiotherapy with oral corticosteroid was started simultaneously leading to full remission but with steroid dependency; 5 days after finishing prednisone, orbital cellulitis symptoms reappeared. The same treatment protocol was given but with corticosteroid tapering over weeks. Nevertheless, steroid dependency persisted. Except for the inflammatory syndrome, complete biological examinations did not disclose any abnormalities. The patient underwent maxillary sinus and fat orbital biopsy; however, histopathological examination was not contributory. Persistence of steroid dependency, chronic atypical rhinosinusitis, normal paraclinical investigations, and age of patient let us suspect lymphoma origin hidden by chronic corticosteroid. We carried out for the second time a maxillary sinus biopsy after stopping steroids, which disclosed primitive non-Hodgkin lymphoma of the maxillary sinus. The aim of this observation is firstly to evoke though it is exceptional the diagnosis of maxillary lymphoma in case of atypical orbital cellulitis and secondly to incite clinicians to be more vigilant in prescribing corticosteroid even if there is an emergency character of orbital cellulitis.
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issn 2090-6722
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spelling doaj-art-5a96a91e61cf448e9156e6caf34d4fb42025-02-03T06:46:00ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302020-01-01202010.1155/2020/23048612304861To What Extent Can Orbital Cellulitis Emergency Aspect Influence the Diagnosis of Maxillary Sinus Lymphoma?Yousra Ajhoun0Ismail Aissa1Taoufik Abdellaoui2Yasmine Chaoui Roqai3Ilias Benchafai4Redouan Messaoudi5Rachid Zerrouk6Karim Reda7Abdelbarre Oubaaz8Ophthalmology Department, Military Instruction Hospital Mohammed V, Rabat, MoroccoAnesthesiology and Intensive Care Department, Military Instruction Hospital Mohammed V, Rabat, MoroccoOphthalmology Department, Military Instruction Hospital Mohammed V, Rabat, MoroccoOphthalmology Department, Military Instruction Hospital Mohammed V, Rabat, MoroccoENT Department, Military Instruction Hospital Mohammed V, Rabat, MoroccoOphthalmology Department, Military Instruction Hospital Mohammed V, Rabat, MoroccoOphthalmology Department, Military Instruction Hospital Mohammed V, Rabat, MoroccoOphthalmology Department, Military Instruction Hospital Mohammed V, Rabat, MoroccoOphthalmology Department, Military Instruction Hospital Mohammed V, Rabat, MoroccoWe present a case of a 46-year-old woman admitted to the emergency department for acute swelling and erythema of the right eyelid for 3 days. Ophthalmological examination was notable for 10/10, P2 best visual acuity, and inflammatory periorbital edema, without exophthalmia nor extraocular motility disturbance. Intraocular pressure was 14 mmHg and fundoscopic examination was not notable for any abnormality. Preseptal cellulitis diagnosis was made, and oral antibiotherapy was immediately started; after 72 hours, the patient did not improve and started complaining of pain on ocular movements. Brain and orbit MRI scan revealed right retroseptal cellulitis associated with homolateral pansinusitis. Intravenous antibiotherapy with oral corticosteroid was started simultaneously leading to full remission but with steroid dependency; 5 days after finishing prednisone, orbital cellulitis symptoms reappeared. The same treatment protocol was given but with corticosteroid tapering over weeks. Nevertheless, steroid dependency persisted. Except for the inflammatory syndrome, complete biological examinations did not disclose any abnormalities. The patient underwent maxillary sinus and fat orbital biopsy; however, histopathological examination was not contributory. Persistence of steroid dependency, chronic atypical rhinosinusitis, normal paraclinical investigations, and age of patient let us suspect lymphoma origin hidden by chronic corticosteroid. We carried out for the second time a maxillary sinus biopsy after stopping steroids, which disclosed primitive non-Hodgkin lymphoma of the maxillary sinus. The aim of this observation is firstly to evoke though it is exceptional the diagnosis of maxillary lymphoma in case of atypical orbital cellulitis and secondly to incite clinicians to be more vigilant in prescribing corticosteroid even if there is an emergency character of orbital cellulitis.http://dx.doi.org/10.1155/2020/2304861
spellingShingle Yousra Ajhoun
Ismail Aissa
Taoufik Abdellaoui
Yasmine Chaoui Roqai
Ilias Benchafai
Redouan Messaoudi
Rachid Zerrouk
Karim Reda
Abdelbarre Oubaaz
To What Extent Can Orbital Cellulitis Emergency Aspect Influence the Diagnosis of Maxillary Sinus Lymphoma?
Case Reports in Ophthalmological Medicine
title To What Extent Can Orbital Cellulitis Emergency Aspect Influence the Diagnosis of Maxillary Sinus Lymphoma?
title_full To What Extent Can Orbital Cellulitis Emergency Aspect Influence the Diagnosis of Maxillary Sinus Lymphoma?
title_fullStr To What Extent Can Orbital Cellulitis Emergency Aspect Influence the Diagnosis of Maxillary Sinus Lymphoma?
title_full_unstemmed To What Extent Can Orbital Cellulitis Emergency Aspect Influence the Diagnosis of Maxillary Sinus Lymphoma?
title_short To What Extent Can Orbital Cellulitis Emergency Aspect Influence the Diagnosis of Maxillary Sinus Lymphoma?
title_sort to what extent can orbital cellulitis emergency aspect influence the diagnosis of maxillary sinus lymphoma
url http://dx.doi.org/10.1155/2020/2304861
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