The dual role of titanium particles in osteolysis: implications for gene therapy in prosthesis loosening
Abstract Background Aseptic prosthesis loosening caused by wear particles is a major complication in patients with osteoarthritis following total joint replacement. Despite advancements in treatment, the underlying mechanisms remain poorly understood, and effective therapies are still lacking. Metho...
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| Main Authors: | Ping Chen, Hao-Hui Guo, Long Wu, Shuai Zhang, Qun-Hua Jin, Ke-Ning Sun |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40001-025-02452-3 |
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