The dual role of titanium particles in osteolysis: implications for gene therapy in prosthesis loosening

Abstract Background Aseptic prosthesis loosening caused by wear particles is a major complication in patients with osteoarthritis following total joint replacement. Despite advancements in treatment, the underlying mechanisms remain poorly understood, and effective therapies are still lacking. Metho...

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Bibliographic Details
Main Authors: Ping Chen, Hao-Hui Guo, Long Wu, Shuai Zhang, Qun-Hua Jin, Ke-Ning Sun
Format: Article
Language:English
Published: BMC 2025-03-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02452-3
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