Genome‐wide allele‐ and strand‐specific expression profiling

Abstract Recent reports have shown that most of the genome is transcribed and that transcription frequently occurs concurrently on both DNA strands. In diploid genomes, the expression level of each allele conditions the degree to which sequence polymorphisms affect the phenotype. It is thus essentia...

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Bibliographic Details
Main Authors: Julien Gagneur, Himanshu Sinha, Fabiana Perocchi, Richard Bourgon, Wolfgang Huber, Lars M Steinmetz
Format: Article
Language:English
Published: Springer Nature 2009-06-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.1038/msb.2009.31
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