Self-assembled vesicles containing podophyllotoxin covalently modified with polyoxometalates for antitumor therapy

Several polyoxometalates (POMs) have been shown to possess antitumor activity. In this study, hydrophilic POMs were combined with the hydrophobic drug podophyllotoxin (PPT) to create an amphiphilic anti-cancer drug PPT-POM-PPT, which can self-assemble into hollow vesicles. The properties of these ve...

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Bibliographic Details
Main Authors: Lingmei Li, Yixiang Song, Jinyu Liu, Quanfu Wang, Jiacheng Wu, Xiaochuan Lu, Dejin Zang, Teng Liu
Format: Article
Language:English
Published: Tsinghua University Press 2025-06-01
Series:Polyoxometalates
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Online Access:https://www.sciopen.com/article/10.26599/POM.2025.9140085
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