Accuracy and consequences of using trial-of-antibiotics for TB diagnosis (ACT-TB study): protocol for a randomised controlled clinical trial

Accuracy and consequences of using trial-of-antibiotics for TB diagnosis (ACT-TB study): protocol for a randomised controlled clinical trial

Introduction Over 40% of global tuberculosis case notifications are diagnosed clinically without mycobacteriological confirmation. Standard diagnostic algorithms include ‘trial-of-antibiotics’—empirical antibiotic treatment given to mycobacteriology-negative individuals to treat infectious causes of...

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Main Authors: Neil French, Peter MacPherson, Titus Henry Divala, Katherine L Fielding, Marriott Nliwasa, Chikondi Charity Kandulu, Lingstone Chiume, Sanderson Chilanga, Masiye John Ndaferankhande
Format: Article
Language:English
Published: BMJ Publishing Group 2020-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/3/e033999.full
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https://bmjopen.bmj.com/content/10/3/e033999.full

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