The acidic microenvironment promotes pancreatic cancer progression via the lncRNA-LOC100507424/E2F1/FOXM1 axis

The acidic microenvironment promotes pancreatic cancer progression via the lncRNA-LOC100507424/E2F1/FOXM1 axis

Abstract Pancreatic cancer is highly aggressive and sensitive to acidic microenvironments, which promote cancer cell survival and invasion. Long non-coding RNAs (lncRNAs) play crucial roles in cancer biology, helping cells adapt to microenvironmental changes, but their functions in the acidic microe...

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Bibliographic Details
Main Authors: Deyang Mu, Ying Shi, Runxuan Sun, Bing Han, Kai Zhong, Yilu Ye, Jungang Zhang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
Subjects:
Pancreatic cancer
Acidic microenvironment
LncRNA
LOC100507424
Cancer progression
Online Access:https://doi.org/10.1186/s12885-025-14073-4
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https://doi.org/10.1186/s12885-025-14073-4

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