Stannous fluoride protects gingival keratinocytes against infection and oxidative stress by Porphyromonas gingivalis outer membrane vesicles

Stannous fluoride protects gingival keratinocytes against infection and oxidative stress by Porphyromonas gingivalis outer membrane vesicles

ObjectiveTo determine whether outer membrane vesicles (OMVs) of the periodontal pathogen Porphyromonas gingivalis (P. gingivalis) can infect gingival keratinocytes and stimulate reactive oxygen species (ROS) production, and to assess whether stannous fluoride (SnF2), stannous chloride (SnCl2) or 0.4...

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Bibliographic Details
Main Authors: Sancai Xie, Cheryl S. Tansky, Julie Ashe, Fei Gao, Nivedita B. Ramji, Vighter Iberi, Yiping Sun, Niranjan Ramji, Aaron R. Biesbrock
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Dental Medicine
Subjects:
stannous fluoride
antibacterial agents
reactive oxygen species
Porphyromonas gingivalis
keratinocyte infection
periodontal diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fdmed.2024.1492369/full
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https://www.frontiersin.org/articles/10.3389/fdmed.2024.1492369/full

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