A computational and experimental approach to studying NFkB signaling in response to single, dual, and triple TLR signaling
Modeling and experimental data were used to evaluate how monocytes would respond to dual TLR4/TLR5 and dual TLR4/TLR7 signaling analogous to how the cells would respond to simultaneously encountering different types of pathogens. Both TLR4/TLR5 and TLR4/TLR7 signaling resulted in a decreased NFkB re...
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| Main Authors: | Thalia Newman, Annarose Taylor, Sakhi Naik, Swati Pandey, Kimberly Manalang, Robert A. Kurt, Chun Wai Liew |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-03-01
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| Series: | ImmunoInformatics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667119024000016 |
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