A computational and experimental approach to studying NFkB signaling in response to single, dual, and triple TLR signaling

A computational and experimental approach to studying NFkB signaling in response to single, dual, and triple TLR signaling

Modeling and experimental data were used to evaluate how monocytes would respond to dual TLR4/TLR5 and dual TLR4/TLR7 signaling analogous to how the cells would respond to simultaneously encountering different types of pathogens. Both TLR4/TLR5 and TLR4/TLR7 signaling resulted in a decreased NFkB re...

Full description

Saved in:
Bibliographic Details
Main Authors: Thalia Newman, Annarose Taylor, Sakhi Naik, Swati Pandey, Kimberly Manalang, Robert A. Kurt, Chun Wai Liew
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:ImmunoInformatics
Subjects:
Computer modeling
Dual and triple TLR signaling
interconnected cascades
Online Access:http://www.sciencedirect.com/science/article/pii/S2667119024000016
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2667119024000016

Similar Items