A Phase 1 randomized trial of homologous and heterologous filovirus vaccines with a late booster dose

A Phase 1 randomized trial of homologous and heterologous filovirus vaccines with a late booster dose

Abstract Filoviruses, including Ebola, Marburg, Sudan, and Taï Forest viruses, are zoonotic pathogens that can cause severe viral hemorrhagic fever and death. Developing vaccines that provide durable, broad immunity against multiple filoviruses is a high global health priority. In this Phase 1 trial...

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Main Authors: Christina A. Rostad, Inci Yildirim, Carol Kao, Jumi Yi, Satoshi Kamidani, Etza Peters, Kathleen Stephens, Theda Gibson, Hui-Mien Hsiao, Karnail Singh, Paul Spearman, Courtney McCracken, Vivien Agbakoba, Kay M. Tomashek, Johannes B. Goll, Casey E. Gelber, Robert A. Johnson, Sujin Lee, Kristal Maner-Smith, Steven Bosinger, Eric A. Ortlund, Xuemin Chen, Larry J. Anderson, Jens Wrammert, Mehul Suthar, Nadine Rouphael, Evan J. Anderson
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-01042-4
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https://doi.org/10.1038/s41541-024-01042-4

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