Xenograft of bio-3D printed scaffold-free cartilage constructs derived from human iPSCs to regenerate articular cartilage in immunodeficient pigs

Xenograft of bio-3D printed scaffold-free cartilage constructs derived from human iPSCs to regenerate articular cartilage in immunodeficient pigs

Arthroplasty is currently the only option for reconstruction of large articular cartilage defects, mainly due to osteoarthritis. However, reconstruction with artificial materials has several issues such as deterioration, foreign body reaction, and bacterial infection. This study established a new me...

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Bibliographic Details
Main Authors: Toshihiro Nonaka, Anna Nakamura, Daiki Murata, Hiromu Yoshizato, Shohei Kashimoto, Yukiko Nagaishi, Manabu Itoh, Denise Zujur, Chengzhu Zhao, Yoshiko Inada, Makoto Ikeya, Junya Toguchida, Masaaki Mawatari, Koichi Nakayama
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Regenerative Therapy
Subjects:
Cartilage regeneration
Bio-3d printer
Scaffold-free
Tissue engineering
iPSC
Articular cartilage
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320425000938
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