Association between pan-immune-inflammation value and Serum Klotho levels: a cross-sectional analysis of renal function mediation

IntroductionKlotho has emerged as a promising biomarker of aging processes. Although inflammation is known to modulate Klotho expression, the relationship between Pan-Immune-Inflammation Value (PIV) and serum Klotho levels has not been investigated. This study aimed to examine the association betwee...

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Bibliographic Details
Main Authors: Mingjie Liu, Xuan Zhou, Han Xu, Yan Wang, Yuting Duan, Xiangru Guo, Bai Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567367/full
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