DLK1 and DLK2, two non-canonical ligands of NOTCH receptors, differentially modulate the osteogenic differentiation of mesenchymal C3H10T1/2 cells

DLK1 and DLK2, two non-canonical ligands of NOTCH receptors, differentially modulate the osteogenic differentiation of mesenchymal C3H10T1/2 cells

Abstract Background C3H10T1/2 is a mesenchymal cell line capable of differentiating into osteoblasts, adipocytes and chondrocytes. The differentiation of these cells into osteoblasts is modulated by various transcription factors, such as RUNX2. Additionally, several interconnected signaling pathways...

Full description

Saved in:
Bibliographic Details
Main Authors: María-Milagros Rodríguez-Cano, María-Julia González-Gómez, Eva-María Monsalve, María-José M. Díaz-Guerra, Moustapha Kassem, Jorge Laborda, María-Luisa Nueda, Victoriano Baladrón
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Biological Research
Subjects:
DLK
NOTCH
Mesenchymal C3H10T1/2 cells
Osteogenesis
ERK1/2 MAPK
p38 MAPK
Online Access:https://doi.org/10.1186/s40659-024-00561-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s40659-024-00561-7

Similar Items