A chemogenetic technology using insect Ionotropic Receptors to stimulate target cell populations in the mammalian brain

Chemogenetics uses artificially-engineered proteins to modify the activity of cells, notably neurons, in response to small molecules. Although a common set of chemogenetic tools are the G protein-coupled receptor-based DREADDs, there has been great hope for ligand-gated, ion channel-type chemogeneti...

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Bibliographic Details
Main Authors: Yoshio Iguchi, Richard Benton, Kazuto Kobayashi
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Neuroscience Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0168010224001366
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