Anti-inflammatory effects of 64Zn-aspartate is accompanied by cognitive improvements in rats with Aβ1-40-induced alzheimer disease

Anti-inflammatory effects of 64Zn-aspartate is accompanied by cognitive improvements in rats with Aβ1-40-induced alzheimer disease

Abstract Alzheimer disease (AD) is a debilitating progressive dementia, whose pathophysiology is not fully understood. Chronic inflammation is now widely accepted as one of the key features of AD pathogenesis. Because of this, anti-inflammatory preparations are considered as putative disease modifyi...

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Bibliographic Details
Main Authors: Max Temnik, Mariia Rudyk, Alexandr Balakin, Sergey Gurin, Taisa Dovbynchuk, Roman Byshovets, Nataliia Dzubenko, Ganna Tolstanova, Larysa Skivka
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Alzheimer disease
Stable light isotope enriched zinc aspartate
Anti-inflammatory agent
Inflammation
Neuroinflammation
Cognitive improvement
Online Access:https://doi.org/10.1038/s41598-025-97830-6
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https://doi.org/10.1038/s41598-025-97830-6

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