The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.

Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to (Coronavirus) CoV epidemics. Neither vaccines nor...

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Main Authors: Susanne Pfefferle, Julia Schöpf, Manfred Kögl, Caroline C Friedel, Marcel A Müller, Javier Carbajo-Lozoya, Thorsten Stellberger, Ekatarina von Dall'Armi, Petra Herzog, Stefan Kallies, Daniela Niemeyer, Vanessa Ditt, Thomas Kuri, Roland Züst, Ksenia Pumpor, Rolf Hilgenfeld, Frank Schwarz, Ralf Zimmer, Imke Steffen, Friedemann Weber, Volker Thiel, Georg Herrler, Heinz-Jürgen Thiel, Christel Schwegmann-Wessels, Stefan Pöhlmann, Jürgen Haas, Christian Drosten, Albrecht von Brunn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002331&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002331&type=printable

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