Efficacy and safety of Bio 3D conduits composed of human umbilical cord–derived mesenchymal stromal cells: A proof-of-concept study in a canine ulnar nerve defect model

Peripheral nerve injuries involving nerve defects remain challenging to treat. Although autologous nerve grafting is considered the gold standard, it has notable limitations, including donor site morbidity. To address this, we developed a scaffold-free Bio 3D conduit composed of human umbilical cord...

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Main Authors: Kazuaki Fujita, Ryosuke Ikeguchi, Tomoki Aoyama, Takashi Noguchi, Koichi Yoshimoto, Daichi Sakamoto, Terunobu Iwai, Tetsuya Miyamoto, Yudai Miyazaki, Shizuka Akieda, Tokiko Nagamura-Inoue, Fumitaka Nagamura, Koichi Nakayama, Shuichi Matsuda
Format: Article
Language:English
Published: SAGE Publishing 2025-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897251361711
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