Single-cell light-sheet fluorescence 3D images of tumour-stroma spheroid multicultures

Abstract Spheroids are widely used in oncology for testing drugs, but models composed of a single cell line do not fully capture the complexity of the in vivo tumours targeted by chemotherapy. Developing 3D in vitro models that better mimic tumour architecture is a crucial step for the scientific co...

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Bibliographic Details
Main Authors: Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-04832-0
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