Highly parallel optimisation of chemical reactions through automation and machine intelligence

Abstract We report the development and application of a scalable machine learning (ML) framework (Minerva) for highly parallel multi-objective reaction optimisation with automated high-throughput experimentation (HTE). Minerva demonstrates robust performance with experimental data-derived benchmarks...

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Bibliographic Details
Main Authors: Joshua W. Sin, Siu Lun Chau, Ryan P. Burwood, Kurt Püntener, Raphael Bigler, Philippe Schwaller
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61803-0
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