Eleutheroside B alleviates oxidative stress and neuroinflammation by inhibiting the JAK2/STAT3 signaling pathway in a rat high altitude cerebral edema model

Eleutheroside B alleviates oxidative stress and neuroinflammation by inhibiting the JAK2/STAT3 signaling pathway in a rat high altitude cerebral edema model

BackgroundHigh altitude cerebral edema (HACE) is a condition where the central nervous system experiences severe impairment as a result of sudden oxygen deprivation at high elevations. At present, effective measures for preventing and treating this condition are still lacking. Eleutheroside B (EB),...

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Bibliographic Details
Main Authors: Yacong He, Hongying Zhang, Xiu Zhang, Yue Han, Huxinyue Duan, Wenqian Song, Qingqing Tian, Yilan Wang, Guang Li, Chunjie Wu, Zhenxing Wang, Tianzhu Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
high altitude cerebral edema
eleutheroside B
oxidative stress
neuroinflammation
JAK2/STAT3 signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1506483/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1506483/full

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