PGE2-Induced IDO1 Inhibits the Capacity of Fully Mature DCs to Elicit an In Vitro Antileukemic Immune Response

In the last years, dendritic cells (DC) have been evaluated for antitumor vaccination. Although DC-based vaccines have raised great expectations, their clinical translation has been largely disappointing. For these results, several explanations have been proposed. In particular,...

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Bibliographic Details
Main Authors: Sara Trabanelli, Mariangela Lecciso, Valentina Salvestrini, Michele Cavo, Darina Očadlíková, Roberto M. Lemoli, Antonio Curti
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2015/253191
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