Tissue-resident Klebsiella quasipneumoniae contributes to progression of idiopathic pulmonary fibrosis by triggering macrophages mitophagy in mice

Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive and chronic interstitial lung disease with unclear underlying pathogenic mechanisms. Dysbiosis of the lung microbiota is believed to be associated with the development of fibrosis; however, the roles of the microbiome in the respiratory f...

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Main Authors: Chunjie Xu, Peiyi Sun, Qiyue Jiang, Yao Meng, Luyao Dong, Xiukun Wang, Xinxin Hu, Congran Li, Guoqing Li, Ruifang Zheng, Xuefu You, Xinyi Yang
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02444-6
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