Comparison of the Efficacy of Adding Inhaled Levofloxacin and Colistin to a Basic Regimen of Colistin and Meropenem in the Treatment of Ventilator-associated Pneumonia Caused by Multidrug-resistant Gram-negative Bacteria: A Randomized Open-label Clinical Trial

Comparison of the Efficacy of Adding Inhaled Levofloxacin and Colistin to a Basic Regimen of Colistin and Meropenem in the Treatment of Ventilator-associated Pneumonia Caused by Multidrug-resistant Gram-negative Bacteria: A Randomized Open-label Clinical Trial

Objective: Ventilator-associated pneumonia (VAP) caused by multidrug-resistant Gram-negative bacteria (MDR-GNB) is a major intensive care unit challenge, particularly in Iran, due to limited antibiotic options. This study compared the efficacy of adding levofloxacin and colistin inhalation form to t...

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Bibliographic Details
Main Authors: Masoumeh Sohrabi, Shahram Ala, Afshin Gholipour-Baradari, Fatemeh Heydari, Alireza Nikzad Jamnani, Mahmoud Mousazadeh, Hamidreza Namvar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Research in Pharmacy Practice
Subjects:
colistin
levofloxacin
multidrug-resistant gram-negative bacteria
ventilator-associated pneumonia
Online Access:https://journals.lww.com/10.4103/jrpp.jrpp_12_25
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