Refractoriness to eltrombopag in adult primary immune thrombocytopenia: utility of next-generation sequencing techniques

Abstract: Thrombopoietin receptor agonists, for example eltrombopag, are standard second-line treatment for immune thrombocytopenia (ITP). Eltrombopag has demonstrated high response rates, both in clinical trials and in routine practice studies. However, some patients with ITP are refractory to this...

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Main Authors: Tomás José González-López, Ricardo Sanchez, Carmen Pastoriza, Pavel Olivera, Silvia Bernat, Fernando Fernandez-Fuertes, Isabel Socorro Caparrós-Miranda, Gloria Pérez-Rus, Isidro Jarque, Maria Esperanza Moreno-Beltrán, Emma López-Abadía, Erik De Cabo, Shally Marcellini, Gloria Pérez-Segura, Carmen Fernández-Miñano, María Jesús Peñarrubia, Sergio Matarraz, María Pérez-Caro, Alberto Orfao, Drew Provan, Joaquín Martínez-López
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Blood Vessels, Thrombosis & Hemostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S295032722500018X
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