Bioactivity-guided fractionation of Withania somnifera (L.) Dunal roots extract: evaluation of the anti-progressive potential on human Kelly neuroblastoma cell line

Bioactivity-guided fractionation of Withania somnifera (L.) Dunal roots extract: evaluation of the anti-progressive potential on human Kelly neuroblastoma cell line

Abstract Background Withania somnifera (L.) Dunal, commonly known as ashwagandha, is a cornerstone of Ayurvedic medicine and has demonstrated anti-metastatic properties, including the ability to mitigate the cytotoxic effects of carcinogens and chemotherapeutic agents. Neuroblastoma (NB), a highly a...

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Bibliographic Details
Main Authors: Nada Ahmad Al-Hasawi, Naser Faisal Al-Tannak, Josily Joy, Khaled Youssef Orabi
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Neuroblastoma
Withania somnifera
Kelly cell line
ECM invasion assay
Fibronectin adhesion assay
Bioactivity-guided fractionation
Online Access:https://doi.org/10.1186/s12906-025-05018-2
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https://doi.org/10.1186/s12906-025-05018-2

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