Development and validation of a CT algorithm based on intratumoral necrosis and tumor morphology to predict the nuclear grade of small (2–4 cm) solid clear cell renal cell carcinoma

Abstract Background Preoperative non-invasive prediction of the World Health Organization/International Society of Urological Pathology (WHO/ISUP) nuclear grade of small clear cell renal cell carcinoma (ccRCC) can aid in decision making for active surveillance. The study aimed to develop and validat...

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Bibliographic Details
Main Authors: Jianyi Qu, Pingyi Zhu, Xianli Zhu, Xinyan Li, Wenjie Zhang, Xinhong Song, Xiaofei Wang, Chenchen Dai, Qianqian Zhang, Jianjun Zhou
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Medical Imaging
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Online Access:https://doi.org/10.1186/s12880-025-01741-x
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