LPA<sub>3</sub>: Pharmacodynamic Differences Between Lysophosphatidic Acid and Oleoyl-Methoxy Glycerophosphothionate: Biased Agonism, Two Sites

LPA<sub>3</sub>: Pharmacodynamic Differences Between Lysophosphatidic Acid and Oleoyl-Methoxy Glycerophosphothionate: Biased Agonism, Two Sites

<b>Background:</b> Lysophosphatidic acid (LPA) receptor 3 (LPA<sub>3</sub>) is involved in many physiological and pathophysiological actions of this bioactive lipid, particularly in cancer. The actions of LPA and oleoyl-methoxy glycerophosphothionate (OMPT) were compared in L...

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Bibliographic Details
Main Authors: K. Helivier Solís, M. Teresa Romero-Ávila, Ruth Rincón-Heredia, Juan Carlos Martínez-Morales, J. Adolfo García-Sáinz
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Receptors
Subjects:
lysophosphatidic acid
LPA
LPA<sub>3</sub> receptor
oleoyl-methoxy glycerophosphothionate
OMPT
biased agonism
Online Access:https://www.mdpi.com/2813-2564/3/4/29
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