Umbilical Cord‐Mesenchymal Stromal Cell‐Derived Extracellular Vesicles Target the Liver to Improve Neurovascular Health in Type 2 Diabetes With Non‐Alcoholic Fatty Liver Disease

Umbilical Cord‐Mesenchymal Stromal Cell‐Derived Extracellular Vesicles Target the Liver to Improve Neurovascular Health in Type 2 Diabetes With Non‐Alcoholic Fatty Liver Disease

ABSTRACT Type 2 diabetes mellitus (T2DM) combined with non‐alcoholic fatty liver disease (NAFLD) exacerbates metabolic dysregulation and neurovascular complications, presenting significant therapeutic challenges. We demonstrate, using SPECT/CT imaging, that extracellular vesicles (EVs) from mesenchy...

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Main Authors: Minghao Du, Hao Yang, Jinyun Niu, Jing Huang, Lihong Wang, Junxiu Xi, Panpan Meng, Zhiyong Liu, Guaiguai Ma, Jiani Li, Xiaoyan Liu, Liang Guo, Mingjun Hu, Zhufang Tian, Bin Liu, Weiping Liu, Ashok K. Shetty, Shengxi Wu, Andrius Baskys, Qianfa Long
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of Extracellular Vesicles
Subjects:
cross‐organ
extracellular vesicles
NAFLD
neurovascular complications
PDGFB
type 2 diabetes mellitus
Online Access:https://doi.org/10.1002/jev2.70125
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https://doi.org/10.1002/jev2.70125

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