Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model

IntroductionNephropathic cystinosis is a rare genetic disorder characterized by cystine accumulation in lysosomes that causes early renal dysfunction and progressive chronic kidney disease. Although several metabolic pathways, including oxidative stress and inflammation, have been implicated in the...

Full description

Saved in:

Bibliographic Details
Main Authors:	M. N. Rossi, A. Ciolfi, V. Matteo, L. Pedace, C. Nardini, E. Loricchio, I. Caiello, F. Bellomo, A. Taranta, E. De Leo, M. Tartaglia, F. Emma, F. De Benedetti, E. Miele, G. Prencipe
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	cystinosis DNA methylation solute carrier genes kidney disease proximal tubular epithelial cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1638123/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!

Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model

Similar Items