The role of complement in the immunopathogenesis of acetylcholine receptor antibody-positive generalized myasthenia gravis: bystander or key player?

The role of complement in the immunopathogenesis of acetylcholine receptor antibody-positive generalized myasthenia gravis: bystander or key player?

The complement system is a key component of the innate immune system. In antiacetylcholine receptor (AChR) antibody-positive (Ab+) generalized myasthenia gravis (MG), complement activation has long been considered a principal driver of pathology. Understanding the role of complement in AChR-Ab+ gene...

Full description

Saved in:
Bibliographic Details
Main Authors: Iliana Michailidou, Anastasia Patsiarika, Evangelia Kesidou, Marina Kleopatra Boziki, Dimitrios Parisis, Christos Bakirtzis, Elisabeth Chroni, Nikolaos Grigoriadis
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
myasthenia gravis
complement system
anti-acetylcholine receptor antibodies
membrane attack complex
therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1526317/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1526317/full

Similar Items